AGXT2 antibody (Internal Region)

Catalog No. ABIN6259832

Product Details anti-AGXT2 Antibody

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: AGXT2 Antibody detects endogenous levels of total AGXT2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AGXT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Alternative Name: AGXT2 (AGXT2 Products)

Synonyms: AGT2 antibody, DAIBAT antibody, AI303810 antibody, AI663818 antibody, T19P19.50 antibody, T19P19_50 antibody, alanine:glyoxylate aminotransferase 2 antibody, im:7153274 antibody, zgc:114195 antibody, alanine--glyoxylate aminotransferase 2 antibody, alanine-glyoxylate aminotransferase 2 antibody, alanine:glyoxylate aminotransferase 2 antibody, AGXT2 antibody, Agxt2 antibody, AGT2 antibody, agxt2 antibody

Background:

Description: Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.

Gene: AGXT2

Molecular Weight: 57 kDa

Gene ID: 64902

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process