APLP1 antibody (Internal Region)

Catalog No. ABIN6259980

Product Details anti-APLP1 Antibody

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: APLP1 Antibody detects endogenous levels of total APLP1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APLP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Alternative Name: APLP1 (APLP1 Products)

Synonyms: aplp antibody, MGC115336 antibody, APLP antibody, Aplp1_retired antibody, RGD1561211 antibody, amyloid beta precursor like protein 1 antibody, amyloid beta precursor like protein 1 L homeolog antibody, amyloid beta (A4) precursor-like protein 1 antibody, APLP1 antibody, aplp1.L antibody, aplp1 antibody, Aplp1 antibody

Background:

Description: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Gene: APLP1

Molecular Weight: 72kD

Gene ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process