Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

APOBEC3A/B antibody

APOBEC3A_B Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259985
  • Target See all APOBEC3A/B (APOBEC3A_B) Antibodies
    APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))
    Reactivity
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOBEC3A/B antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Specificity
    APOBEC3A/B Antibody detects endogenous levels of total APOBEC3A/B
    Cross-Reactivity
    Human
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human APOBEC3A/B
    Isotype
    IgG
  • Application Notes
    WB 1:1000-3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))
    Alternative Name
    APOBEC3A/B (APOBEC3A_B Products)
    Synonyms
    A3A antibody, APOBEC3A and APOBEC3B deletion hybrid antibody, APOBEC3A_B antibody
    Background

    Description: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

    Gene: APOBEC3A

    Molecular Weight
    23 kDa,46 kDa
    Gene ID
    100, 913, 187
    UniProt
    P31941, Q9UH17
Support