CNOT10 antibody (Internal Region)

Catalog No. ABIN6260913

The Rabbit Polyclonal anti-CNOT10 antibody is suitable to detect CNOT10 in samples from Human and Mouse. It has been validated for WB, IHC, IF and ICC.

Quick Overview for CNOT10 antibody (Internal Region) (ABIN6260913)

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CNOT10 Antibody

Binding Specificity: Internal Region

Purpose: CNOT10 Antibody

Specificity: CNOT10 Antibody detects endogenous levels of total CNOT10.

Predicted Reactivity: Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNOT10, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CNOT10

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Alternative Name: CNOT10

Background:

Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.

Gene: CNOT10

Molecular Weight: 82 kDa

Gene ID: 25904

UniProt: Q9H9A5