NPPC antibody (Internal Region)

Catalog No. ABIN6260915

Product Details anti-NPPC Antibody

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: CNP-53 Antibody detects endogenous levels of total CNP-53.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNP-53, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NPPC

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Alternative Name: NPPC (NPPC Products)

Synonyms: CNPF antibody, CNPI antibody, CNPII antibody, Cnp1 antibody, CNP antibody, lbab antibody, CNP2 antibody, CNP3 antibody, cnp antibody, nppc antibody, 2',3'-cyclic nucleotide 3' phosphodiesterase antibody, natriuretic peptide type C antibody, natriuretic peptide C antibody, natriuretic peptide C S homeolog antibody, Cnp antibody, Nppc antibody, NPPC antibody, nppc.S antibody

Background:

Description: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity).

Gene: NPPC

Molecular Weight: 13 kDa

Gene ID: 4880

UniProt: P23582