COL8A1 antibody (Internal Region)

Catalog No. ABIN6260950

Product Details anti-COL8A1 Antibody

Target: COL8A1 (Collagen, Type VIII, alpha 1 (COL8A1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL8A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Collagen VIII alpha 1 Antibody detects endogenous levels of total Collagen VIII alpha 1.

Predicted Reactivity: Pig,Horse,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Collagen VIII alpha 1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for COL8A1

Target: COL8A1 (Collagen, Type VIII, alpha 1 (COL8A1))

Alternative Name: COL8A1 (COL8A1 Products)

Synonyms: COL8A1 antibody, Col8a-1 antibody, C3orf7 antibody, collagen type VIII alpha 1 chain antibody, collagen, type VIII, alpha 1 S homeolog antibody, collagen, type VIII, alpha 1 antibody, COL8A1 antibody, col8a1.S antibody, Col8a1 antibody

Background:

Description: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

Gene: COL8A1

Molecular Weight: 73 kDa

Gene ID: 1295

UniProt: P27658