CXXC5 antibody
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- Target See all CXXC5 Antibodies
- CXXC5 (CXXC Finger Protein 5 (CXXC5))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CXXC5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- CXXC5 antibody detects endogenous levels of CXXC5.
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CXXC5.
- Isotype
- IgG
- Top Product
- Discover our top product CXXC5 Primary Antibody
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anti-CXXC Finger Protein 5 (CXXC5) (AA 1-227) antibody
CXXC5 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-CXXC Finger Protein 5 (CXXC5) (AA 47-80) antibodyCXXC5 Reactivity: Human WB Host: Rabbit Polyclonal RB54258 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- CXXC5 (CXXC Finger Protein 5 (CXXC5))
- Alternative Name
- CXXC5 (CXXC5 Products)
- Synonyms
- 4930415K17Rik antibody, CF5 antibody, RINF antibody, WID antibody, CXXC finger 5 antibody, CXXC finger protein 5 antibody, Cxxc5 antibody, CXXC5 antibody
- Background
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Description: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4 % oxygen), as well as normoxia conditions (20 % oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).
Gene: CXXC5
- Molecular Weight
- 35-40 kDa
- Gene ID
- 51523
- UniProt
- Q7LFL8
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