DIO1 antibody (C-Term)
Quick Overview for DIO1 antibody (C-Term) (ABIN6261300)
Target
See all DIO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- DIO1 Antibody detects endogenous levels of total DIO1.
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Predicted Reactivity
- Pig,Sheep,Rabbit,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human DIO1, corresponding to a region within C-terminal amino acids.
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Isotype
- IgG
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anti-Deiodinase, Iodothyronine, Type I (DIO1) antibody
DIO1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type I (DIO1) (AA 30-57), (N-Term) antibodyDIO1 Reactivity: Human WB Host: Rabbit Polyclonal RB21147 unconjugated
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))
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Alternative Name
- DIO1
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Background
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Description: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
Gene: DIO1
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Molecular Weight
- 13 kDa, 29 kDa
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Gene ID
- 1733
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UniProt
- P49895
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Pathways
- Hormone Activity
Target
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