DIO1 antibody (AA 34-249) (Biotin)

Catalog No. ABIN7173961

Product Details anti-DIO1 Antibody (Biotin)

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Binding Specificity: AA 34-249

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Type I iodothyronine deiodinase protein (34-249AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DIO1

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Alternative Name: DIO1 (DIO1 Products)

Synonyms: 5DI antibody, TXDI1 antibody, ITDI1 antibody, D1 antibody, DIOI antibody, Deio1 antibody, cb685 antibody, zgc:92323 antibody, iodothyronine deiodinase 1 antibody, type I iodothyronine deiodinase-like antibody, deiodinase, iodothyronine, type I antibody, deiodinase, iodothyronine type 1 L homeolog antibody, DIO1 antibody, LOC100231867 antibody, Dio1 antibody, dio1.L antibody, dio1 antibody

Background:

Background: Responsible for the deiodination of T4 (3,5,3\',5\'-tetraiodothyronine) into T3 (3,5,3\'-triiodothyronine) and of T3 into T2 (3,3\'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Aliases: DIO1 antibody, ITDI1 antibody, TXDI1 antibody, Type I iodothyronine deiodinase antibody, EC 1.21.99.4 antibody, 5DI antibody, DIOI antibody, Type 1 DI antibody, Type-I 5'-deiodinase antibody

UniProt: P49895

Pathways: Hormone Activity