DIO1 antibody

Catalog No. ABIN7113399

The Rabbit Polyclonal anti-DIO1 antibody (ABIN7113399) specifically detects DIO1 in ELISA, WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DIO1 antibody (ABIN7113399)

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DIO1 Antibody

Purpose: DIO1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: deiodinase, iodothyronine, type I

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DIO1

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Alternative Name: DIO1

Background:

Synonyms: Type I iodothyronine deiodinase|5DI|DIOI|Type 1 DI|Type-I 5'-deiodinase|DIO1|ITDI1|TXDI1

Background: Responsible for the deiodination of T4(3,5,3',5'-tetraiodothyronine) into T3(3,5,3'-triiodothyronine) and of T3 into T2(3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Molecular Weight: 13 kDa, 29 kDa

Gene ID: 1733

UniProt: P49895

Pathways: Hormone Activity