DIO1 antibody

Catalog No. ABIN7236774

This Rabbit Polyclonal antibody specifically detects DIO1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DIO1 antibody (ABIN7236774)

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-DIO1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DIDO1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DIO1

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Alternative Name: DIO1

Background: Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.

UniProt: Q9BTC0

Pathways: Hormone Activity