ENTPD5 antibody

Catalog No. ABIN6261545

Product Details anti-ENTPD5 Antibody

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENTPD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: ENTPD5 Antibody detects endogenous levels of total ENTPD5

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ENTPD5

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for ENTPD5

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Alternative Name: ENTPD5 (ENTPD5 Products)

Synonyms: ENTPD5 antibody, CD39L4 antibody, NTPDase-5 antibody, PCPH antibody, AI196558 antibody, AI987697 antibody, Cd39l4 antibody, ER-UDPase antibody, NTPDase5 antibody, Pcph antibody, mNTPase antibody, cph antibody, ectonucleoside triphosphate diphosphohydrolase 5 antibody, ectonucleoside triphosphate diphosphohydrolase 5 L homeolog antibody, ENTPD5 antibody, entpd5 antibody, entpd5.L antibody, Entpd5 antibody

Background:

Description: Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Gene: ENTPD5

Molecular Weight: 47 kDa

Gene ID: 957

UniProt: O75356