GOPC antibody (Internal Region)

Catalog No. ABIN6262034

Product Details anti-GOPC Antibody

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GOPC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: GOPC Antibody detects endogenous levels of total GOPC.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GOPC, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GOPC

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Alternative Name: GOPC (GOPC Products)

Synonyms: DKFZp459H2130 antibody, 2210402P09Rik antibody, AI844555 antibody, CAL antibody, FIG antibody, GOPC1 antibody, PIST antibody, fe38f01 antibody, wu:fe38f01 antibody, zgc:56254 antibody, zgc:65853 antibody, dJ94G16.2 antibody, cal antibody, gopc1 antibody, pist antibody, golgi associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing S homeolog antibody, GOPC antibody, Gopc antibody, gopc antibody, gopc.S antibody

Background:

Description: Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.

Gene: GOPC

Molecular Weight: 51 kDa

Gene ID: 57120

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization