GPSM1 antibody (Internal Region)

Catalog No. ABIN6262064

Product Details anti-GPSM1 Antibody

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPSM1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: GPSM1 Antibody detects endogenous levels of total GPSM1.

Predicted Reactivity: Pig,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPSM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Alternative Name: GPSM1 (GPSM1 Products)

Synonyms: 1810037C22Rik antibody, AW107933 antibody, Ags3 antibody, AGS3 antibody, ags3 antibody, gpsm1 antibody, G-protein signalling modulator 1 (AGS3-like, C. elegans) antibody, G-protein signaling modulator 1 antibody, G protein signaling modulator 1 antibody, G-protein signaling modulator 1 L homeolog antibody, Gpsm1 antibody, GPSM1 antibody, gpsm1.L antibody

Background:

Description: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Gene: GPSM1

Molecular Weight: 75 kDa

Gene ID: 26086

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling