MED24 antibody (C-Term)

Catalog No. ABIN6263193

Product Details anti-MED24 Antibody

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED24 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MED24 Antibody detects endogenous levels of total MED24.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MED24, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MED24

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Alternative Name: MED24 (MED24 Products)

Synonyms: CG7999 antibody, Dmel\\CG7999 antibody, Med24 antibody, Trap100 antibody, dTRAP100 antibody, l(3)psg5 antibody, MED24 antibody, THRAP4 antibody, DpseGA20755 antibody, dpse_GLEANR_1506 antibody, GA20755 antibody, dyak_GLEANR_4540 antibody, DyakGE20715 antibody, GE20715 antibody, dmoj_GLEANR_17526 antibody, DmojGI16770 antibody, GI16770 antibody, dper_GLEANR_4776 antibody, DperGL22535 antibody, GL22535 antibody, dsim_GLEANR_14081 antibody, DsimGD14060 antibody, GD14060 antibody, ARC100 antibody, CRSP100 antibody, CRSP4 antibody, DRIP100 antibody, TRAP100 antibody, 911GSE antibody, AU040102 antibody, AW547152 antibody, D11Ertd307e antibody, Gse2 antibody, Pparb2 antibody, Pparbp2 antibody, R75526 antibody, Thrap4 antibody, fc05c04 antibody, thrap4 antibody, trap100 antibody, wu:fc05c04 antibody, Mediator complex subunit 24 antibody, mediator complex subunit 24 antibody, mediator of RNA polymerase II transcription subunit 24 antibody, GA20755 gene product from transcript GA20755-RA antibody, DyakGE20715-PA antibody, GI16770 gene product from transcript GI16770-RA antibody, GL22535 gene product from transcript GL22535-RA antibody, GD14060 gene product from transcript GD14060-RA antibody, microRNA 6884 antibody, MED24 antibody, LOC100016544 antibody, LOC100398369 antibody, Dpse\Trap100 antibody, DyakTrap100 antibody, Dmoj\Trap100 antibody, Dper\Trap100 antibody, Dsim\Trap100 antibody, Med24 antibody, MIR6884 antibody, med24 antibody

Background:

Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene: MED24

Molecular Weight: 110kDa

Gene ID: 9862

UniProt: O75448

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity