MED24 antibody (AA 939-989)

Catalog No. ABIN7449847

Product Details anti-MED24 Antibody

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Binding Specificity: AA 939-989

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED24 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-TRAP100/MED24 Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken

Purification: Affinity Purified

Immunogen: between AA 939 and 989

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MED24

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Alternative Name: TRAP100/MED24 (MED24 Products)

Synonyms: CG7999 antibody, Dmel\\CG7999 antibody, Med24 antibody, Trap100 antibody, dTRAP100 antibody, l(3)psg5 antibody, MED24 antibody, THRAP4 antibody, DpseGA20755 antibody, dpse_GLEANR_1506 antibody, GA20755 antibody, dyak_GLEANR_4540 antibody, DyakGE20715 antibody, GE20715 antibody, dmoj_GLEANR_17526 antibody, DmojGI16770 antibody, GI16770 antibody, dper_GLEANR_4776 antibody, DperGL22535 antibody, GL22535 antibody, dsim_GLEANR_14081 antibody, DsimGD14060 antibody, GD14060 antibody, ARC100 antibody, CRSP100 antibody, CRSP4 antibody, DRIP100 antibody, TRAP100 antibody, 911GSE antibody, AU040102 antibody, AW547152 antibody, D11Ertd307e antibody, Gse2 antibody, Pparb2 antibody, Pparbp2 antibody, R75526 antibody, Thrap4 antibody, fc05c04 antibody, thrap4 antibody, trap100 antibody, wu:fc05c04 antibody, Mediator complex subunit 24 antibody, mediator complex subunit 24 antibody, mediator of RNA polymerase II transcription subunit 24 antibody, GA20755 gene product from transcript GA20755-RA antibody, DyakGE20715-PA antibody, GI16770 gene product from transcript GI16770-RA antibody, GL22535 gene product from transcript GL22535-RA antibody, GD14060 gene product from transcript GD14060-RA antibody, microRNA 6884 antibody, MED24 antibody, LOC100016544 antibody, LOC100398369 antibody, Dpse\Trap100 antibody, DyakTrap100 antibody, Dmoj\Trap100 antibody, Dper\Trap100 antibody, Dsim\Trap100 antibody, Med24 antibody, MIR6884 antibody, med24 antibody

Background: Background: TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development.

Gene ID: 9862

NCBI Accession: NP_055630

UniProt: O75448

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity