Neurofibromin 1 antibody (C-Term)

Catalog No. ABIN6263619

The Rabbit Polyclonal anti-Neurofibromin 1 antibody is suitable to detect Neurofibromin 1 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB, IF and ICC.

Quick Overview for Neurofibromin 1 antibody (C-Term) (ABIN6263619)

Target: Neurofibromin 1 (NF1)

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurofibromin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Neurofibromin 1 Antibody

Binding Specificity: C-Term

Purpose: NF1 Antibody

Specificity: NF1 Antibody detects endogenous levels of total NF1

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NF1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Neurofibromin 1

Target: Neurofibromin 1 (NF1)

Alternative Name: NF1

Background:

Description: Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.

Gene: NF1

Molecular Weight: 319 kDa

Gene ID: 4763

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity