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NUAK2 antibody (N-Term)
NUAK2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB8576
unconjugated
Product Details anti-NUAK2 Antibody
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Target
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NUAK2
(NUAK Family, SNF1-Like Kinase, 2 (NUAK2))
Binding Specificity
All epitopes for NUAK2 antibodies
AA 67-96, N-Term
Reactivity
All reactivities for NUAK2 antibodies
Human
Host
All hosts for NUAK2 antibodies
Rabbit
Clonality
All clonalities for NUAK2 antibodies
Polyclonal
Conjugate
All conjugates for NUAK2 antibodies
This NUAK2 antibody is un-conjugated
Application
All applications for NUAK2 antibodies
Western Blotting (WB)
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.
Clone
RB8576
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-NUAK2 antibody (ABIN391234)
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Yamamoto, Takashima, Shintani, Yamazaki, Seguchi, Nakano, Higo, Kato, Liao, Asano, Minamino, Matsumura, Takeda, Kitakaze : "Identification of a novel substrate for TNFalpha-induced kinase NUAK2. " in: Biochemical and biophysical research communications , Vol. 365 , Issue 3 , pp. 541-7 , (2008 ) (PubMed ).
Target Details for NUAK2
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Target
NUAK2
(NUAK Family, SNF1-Like Kinase, 2 (NUAK2))
Alternative Name
NUAK2 (NUAK2 Products )
Synonyms
SNARK antibody, 1200013B22Rik antibody, Omphk2 antibody, Snark antibody, mKIAA0537 antibody, 1200013b22rik antibody, UV126 antibody, NUAK family kinase 2 antibody, NUAK family, SNF1-like kinase, 2 antibody, NUAK2 antibody, Nuak2 antibody
Background
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
Molecular Weight
69612
Gene ID
81788
NCBI Accession
NP_112214
UniProt
Q9H093
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