Oligophrenin 1 antibody

Catalog No. ABIN6263819

Product Details anti-Oligophrenin 1 Antibody

Target: Oligophrenin 1 (OPHN1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oligophrenin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Oligophrenin 1 antibody detects endogenous levels of Oligophrenin 1.

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Oligophrenin 1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for Oligophrenin 1

Target: Oligophrenin 1 (OPHN1)

Alternative Name: Oligophrenin 1 (OPHN1 Products)

Synonyms: ARHGAP41 antibody, MRX60 antibody, OPN1 antibody, C130037N19Rik antibody, Opn1 antibody, MGC68856 antibody, zgc:92603 antibody, OPHN1 antibody, mrx60 antibody, opn1 antibody, oligophrenin 1 antibody, oligophrenin 1 L homeolog antibody, OPHN1 antibody, Ophn1 antibody, ophn1.L antibody, ophn1 antibody, Tsp_13482 antibody

Background:

Description: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).

Gene: OPHN1

Molecular Weight: 92 kDa

Gene ID: 4983

UniProt: O60890