RIC8B antibody (C-Term)

Catalog No. ABIN6264754

Product Details anti-RIC8B Antibody

Target: RIC8B (Resistance To Inhibitors of Cholinesterase 8 Homolog B (RIC8B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIC8B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: RIC8B Antibody detects endogenous levels of total RIC8B.

Predicted Reactivity: Zebrafish

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RIC8B, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RIC8B

Target: RIC8B (Resistance To Inhibitors of Cholinesterase 8 Homolog B (RIC8B))

Alternative Name: RIC8B (RIC8B Products)

Synonyms: DKFZp469H2225 antibody, BC051080 antibody, Ric-8 antibody, Ric-8b antibody, RIC8 antibody, hSyn antibody, RIC8 guanine nucleotide exchange factor B antibody, RIC8B antibody, Ric8b antibody

Background:

Description: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction.

Gene: RIC8B

Molecular Weight: 61-66 kDa

Gene ID: 55188

UniProt: Q9NVN3

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling