SENP3 antibody (Internal Region)
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- Target See all SENP3 Antibodies
- SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SENP3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- SENP3 Antibody detects endogenous levels of total SENP3.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SENP3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SENP3 Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
- Alternative Name
- SENP3 (SENP3 Products)
- Synonyms
- SMT3IP1 antibody, SSP3 antibody, Ulp1 antibody, AA408656 antibody, Smt3ip antibody, Smt3ip1 antibody, ssp3 antibody, smt3ip1 antibody, fa03d07 antibody, wu:fa03d07 antibody, senp3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUMO/sentrin specific peptidase 3 antibody, Sumo1/sentrin/SMT3 specific peptidase 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3b antibody, SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog antibody, SENP3 antibody, Senp3 antibody, senp3 antibody, senp3b antibody, senp3.L antibody
- Background
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Description: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Gene: SENP3
- Molecular Weight
- 65 kDa
- Gene ID
- 26168
- UniProt
- Q9H4L4
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