Ubinuclein 1 antibody (Internal Region)

Catalog No. ABIN6265859

This Rabbit Polyclonal antibody specifically detects Ubinuclein 1 in WB, IHC, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Ubinuclein 1 antibody (Internal Region) (ABIN6265859)

Target: Ubinuclein 1 (UBN1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubinuclein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Ubinuclein 1 Antibody

Binding Specificity: Internal Region

Purpose: Ubinuclein Antibody

Specificity: Ubinuclein Antibody detects endogenous levels of total Ubinuclein.

Predicted Reactivity: Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Ubinuclein, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IF/ICC 1:100-1:500,IHC 1:50-1:200,WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Alternative Name: Ubinuclein

Background:

Description: Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.

Gene: UBN1

Molecular Weight: 121 kDa

Gene ID: 29855

UniProt: Q9NPG3