SUMO4 antibody (Internal Region)

Catalog No. ABIN6266276

This Rabbit Polyclonal antibody specifically detects SUMO4 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for SUMO4 antibody (Internal Region) (ABIN6266276)

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SUMO4 Antibody

Binding Specificity: Internal Region

Purpose: SUMO4 Antibody

Specificity: SUMO4 Antibody detects endogenous levels of total SUMO4

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SUMO4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000, IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SUMO4

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Alternative Name: SUMO4

Background:

Description: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.

Gene: SUMO4

Molecular Weight: 12kDa

Gene ID: 387082

UniProt: Q6EEV6