OTUB2 antibody (Internal Region)

Catalog No. ABIN6280893

Product Details anti-OTUB2 Antibody

Target: OTUB2 (OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2))

Binding Specificity: AA 110-190, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: OTUB2 is a protein encoded by the OTUB2 gene which is approximately 27,2 kDa. OTUB2 is localised to the nucleus. It is involved in the metabolism of proteins, deubiquitination and ovarian tumor domain proteases. OTUB2 is one of several deubiquitylating enzymes. It is a hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Ubiquitin modification of proteins is needed for their stability and function. OTUB2 is widely expressed with higher expression in the brain. STJ94840 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of OTUB2 protein.

Specificity: OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.

Characteristics: Rabbit polyclonal to OTUB2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human OTUB2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Comment:

Widely expressed. Expressed at higher level in brain.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for OTUB2

Target: OTUB2 (OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2))

Alternative Name: OTUB2 (OTUB2 Products)

Synonyms: OTUB2 antibody, otb2 antibody, otu2 antibody, C14orf137 antibody, OTB2 antibody, OTU2 antibody, 2010015L18Rik antibody, 4930586I02Rik antibody, AI413508 antibody, AW557219 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 2 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 2 S homeolog antibody, OTU domain, ubiquitin aldehyde binding 2 antibody, OTUB2 antibody, otub2.S antibody, otub2 antibody, Otub2 antibody

Molecular Weight: 27 kDa

Gene ID: 78990

UniProt: Q96DC9