CD63 antibody (Internal Region)

Catalog No. ABIN6281100

Product Details anti-CD63 Antibody

Target: CD63

Binding Specificity: AA 121-170, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD63 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: CD63 is a protein encoded by the CD63 gene which is approximately 25,6 kDa. CD63 is localised to the cell membrane. It is involved in response to elevated platelet cytosolic Ca2+, the innate immune system and adhesion. This protein falls under the tetraspanin family. Most of these members are characterized by the presence of four hydrophobic domains. It is a cell surface glycoprotein that is known to complex with integrins and may function as a blood platelet activation marker. It also mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed in skin, lung, blood, liver and muscle. Mutations in the CD63 gene may result in mast cell disease. STJ96890 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD63 protein.

Specificity: CD63 Polyclonal Antibody detects endogenous levels of CD63 protein.

Characteristics: Rabbit polyclonal to CD63.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CD63.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000

Comment:

Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for CD63

Target: CD63

Alternative Name: CD63 (CD63 Products)

Synonyms: C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody

Gene ID: 967

UniProt: P08962