ARFGAP3 antibody (Internal Region)

Catalog No. ABIN6282789

Product Details anti-ARFGAP3 Antibody

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Binding Specificity: AA 280-360, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFGAP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: ARF GAP3 is a protein encoded by the ARFGAP3 gene which is approximately 56,9 kDa. ARF GAP3 is localised to the cytoplasm and Golgi apparatus membrane. It is involved in transport to the Golgi and subsequent modification, Golgi-to-ER retrograde transport and metabolism of proteins. It associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. ARF GAP3 is widely expressed with the highest expression in endocrine glands and testis. Mutations in the ARFGAP3 gene result in premature menopause. STJ91672 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ARF GAP3 protein.

Specificity: ARF GAP3 Polyclonal Antibody detects endogenous levels of ARF GAP3 protein.

Characteristics: Rabbit polyclonal to ARF GAP3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ARF GAP3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:10000

Comment:

Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ARFGAP3

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Alternative Name: ARF GAP3 (ARFGAP3 Products)

Synonyms: ARFGAP1 antibody, 0610009H19Rik antibody, 1810004P07Rik antibody, 1810035F16Rik antibody, 9130416J18Rik antibody, Arfgap1 antibody, arfgap1 antibody, xgap antibody, zgc:85765 antibody, arfgap3 antibody, ADP ribosylation factor GTPase activating protein 3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody, ADP ribosylation factor GTPase activating protein 3 S homeolog antibody, ARFGAP3 antibody, Arfgap3 antibody, arfgap3 antibody, arfgap3.S antibody

Molecular Weight: 60 kDa

Gene ID: 26286

UniProt: Q9NP61