NOS2 antibody (AA 90-170)
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- Target See all NOS2 Antibodies
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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Binding Specificity
- AA 90-170
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NOS2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- NOS2 is a protein encoded by the NOS2 gene which is approximately 131,1 kDa. NOS2 is localised to the cytoplasm. It is involved in arginine biosynthesis, toxoplasmosis, G-beta gamma signalling and PEDF induced signalling. It is a nitric oxide synthase messenger molecule with diverse functions throughout the body. In macrophages, it mediates tumoricidal and bactericidal actions and is also involved in inflammation by enhancing the synthesis of proinflammatory mediators such as IL6 and IL8. NOS2 is expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Mutations in the NOS2 gene may result in borderline leprosy and Peyronie's disease. STJ94534 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of NOS2 protein.
- Specificity
- NOS2 Polyclonal Antibody detects endogenous levels of NOS2 protein.
- Characteristics
- Rabbit polyclonal to NOS2.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human NOS2 around the non-phosphorylation site of Y151.
- Isotype
- IgG
- Top Product
- Discover our top product NOS2 Primary Antibody
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- Application Notes
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WB 1:500-1:2000
ELISA 1:10000 - Comment
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Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
- Alternative Name
- NOS2 (NOS2 Products)
- Synonyms
- HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody
- Molecular Weight
- 131 kDa
- Gene ID
- 4843
- UniProt
- P35228
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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