FGF17 antibody (Internal Region)

Catalog No. ABIN6287202

Product Details anti-FGF17 Antibody

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Binding Specificity: AA 130-210, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: FGF-13 is a protein encoded by the FGF13 gene which is approximately 27,5 kDa. FGF-13 is localised to the cell membrane, cytoplasm and nucleus. It is involved in apoptotic pathways, GPCR pathway, TGF-Beta pathway and ERK signalling. It is a microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. It also plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. FGF-13 is expressed in the nervous system, eye, kidney, skin and lung. Mutations in the FGF13 gene may result in Borjeson-Forssman-Lehmann syndrome and Wildervanck syndrome. STJ93061 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of FGF-13 protein.

Specificity: FGF-13 Polyclonal Antibody detects endogenous levels of FGF-13 protein.

Characteristics: Rabbit polyclonal to FGF-13.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FGF-13

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:5000

Comment:

Ubiquitously expressed. Predominantly expressed in the nervous system.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for FGF17

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Alternative Name: FGF-13 (FGF17 Products)

Synonyms: FGF17 antibody, FGF-13 antibody, HH20 antibody, fgf17b antibody, zgc:101759 antibody, fibroblast growth factor 17 antibody, FGF17 antibody, Fgf17 antibody, fgf17 antibody

Molecular Weight: 28 kDa

Gene ID: 2258

UniProt: Q92913

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway