ATP6V1H antibody (Internal Region)

Catalog No. ABIN6287269

Product Details anti-ATP6V1H Antibody

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Binding Specificity: AA 310-390, Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1H antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55,9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.

Specificity: V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.

Characteristics: Rabbit polyclonal to V-ATPase H.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human V-ATPase H

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Comment:

Widely expressed.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ATP6V1H

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Alternative Name: V-ATPase H (ATP6V1H Products)

Synonyms: MSTP042 antibody, NBP1 antibody, SFD antibody, SFDalpha antibody, SFDbeta antibody, VMA13 antibody, V-ATPASE antibody, 0710001F19Rik antibody, AU022349 antibody, CGI-11 antibody, chunp6890 antibody, ATPase H+ transporting V1 subunit H antibody, ATPase, H+ transporting, lysosomal V1 subunit H antibody, ATP6V1H antibody, Atp6v1h antibody, atp6v1h antibody

Molecular Weight: 55 kDa

Gene ID: 51606

UniProt: Q9UI12

Pathways: Transition Metal Ion Homeostasis, Proton Transport