SCARB2 antibody

Catalog No. ABIN6290172

Product Details anti-SCARB2 Antibody

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human SCARB2

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:3000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Alternative Name: SCARB2 (SCARB2 Products)

Synonyms: cd36l2 antibody, fi13c07 antibody, chunp6914 antibody, wu:fi13c07 antibody, SCARB2 antibody, scarb2 antibody, AMRF antibody, CD36L2 antibody, EPM4 antibody, HLGP85 antibody, LGP85 antibody, LIMP-2 antibody, LIMPII antibody, SR-BII antibody, 9330185J12Rik antibody, Cd36l2 antibody, MLGP85 antibody, LimpII antibody, scavenger receptor class B, member 2a antibody, scavenger receptor class B member 2 antibody, scavenger receptor class B, member 2 antibody, scarb2a antibody, SCARB2 antibody, scarb2 antibody, Scarb2 antibody

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 54.29 kDa

Gene ID: 950

UniProt: Q14108