CDCA4 antibody

Catalog No. ABIN6290234

Product Details anti-CDCA4 Antibody

Target: CDCA4 (Cell Division Cycle Associated 4 (CDCA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human CDCA4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes, Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon, Hardly detectable, if at all, in the brain, skeletal muscle and heart

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CDCA4

Target: CDCA4 (Cell Division Cycle Associated 4 (CDCA4))

Alternative Name: CDCA4 (CDCA4 Products)

Synonyms: HEPP antibody, SEI-3/HEPP antibody, 2410018C03Rik antibody, SEI-3 antibody, cell division cycle associated 4 antibody, cell division cycle associated 4 L homeolog antibody, CDCA4 antibody, cdca4 antibody, cdca4.L antibody, Cdca4 antibody

Background: This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.

Molecular Weight: 26.114 kDa

Gene ID: 55038

UniProt: Q9BXL8