ADGRE2 antibody

Catalog No. ABIN6290303

Product Details anti-ADGRE2 Antibody

Target: ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADGRE2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human EMR2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expression is restricted to myeloid cells, Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas, Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested, High expression in mast cells

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ADGRE2

Target: ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))

Alternative Name: ADGRE2 (ADGRE2 Products)

Synonyms: CD312 antibody, adhesion G protein-coupled receptor E2 antibody, ADGRE2 antibody

Background: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 90.472 kDa

Gene ID: 30817

UniProt: Q9UHX3