GIMAP5 antibody

Catalog No. ABIN6290420

Product Details anti-GIMAP5 Antibody

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIMAP5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human GIMAP5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed with high levels in lymph node and spleen, High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes, Highly expressed in B-lymphocyte-derived neoplasms

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for GIMAP5

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Alternative Name: GIMAP5 (GIMAP5 Products)

Synonyms: HIMAP3 antibody, IAN-5 antibody, IAN4 antibody, IAN4L1 antibody, IAN5 antibody, IMAP3 antibody, IROD antibody, Ian4l1 antibody, Ian5 antibody, D630024P16 antibody, E230026N22Rik antibody, GTPase, IMAP family member 5 antibody, GTPase IMAP family member 5 antibody, GIMAP5 antibody, Gimap5 antibody, LOC463896 antibody

Background: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Molecular Weight: 34.846 kDa

Gene ID: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response