PADI2 antibody

Catalog No. ABIN6290719

Product Details anti-PADI2 Antibody

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PADI2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PADI2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PADI2

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Alternative Name: PADI2 (PADI2 Products)

Synonyms: PADI2 antibody, PAD-H19 antibody, PAD2 antibody, PDI2 antibody, Pdi antibody, Pdi2 antibody, mKIAA0994 antibody, peptidyl arginine deiminase 2 antibody, peptidyl arginine deiminase, type II antibody, protein-arginine deiminase type-2 antibody, peptidyl arginine deiminase, type II S homeolog antibody, PADI2 antibody, padi2 antibody, LOC100357368 antibody, padi2.S antibody, Padi2 antibody

Background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Molecular Weight: 75.564 kDa

Gene ID: 11240

UniProt: Q9Y2J8