SNX15 antibody

Catalog No. ABIN6290936

Product Details anti-SNX15 Antibody

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX15 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human SNX15

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: SNX15 (SNX15 Products)

Synonyms: SNX15 antibody, hsaf001435 antibody, snx15 antibody, MGC154249 antibody, HSAF001435 antibody, 1500032B08Rik antibody, E130013C21Rik antibody, sorting nexin 15 antibody, sorting nexin 15 S homeolog antibody, SNX15 antibody, snx15.S antibody, snx15 antibody, Snx15 antibody

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Molecular Weight: 38.291 kDa

Gene ID: 29907

UniProt: Q9NRS6