CysLTR1 antibody

Catalog No. ABIN6291346

Product Details anti-CysLTR1 Antibody

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CysLTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CYSLTR1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed, with highest levels in spleen and peripheral blood leukocytes, Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Alternative Name: CYSLTR1 (CYSLTR1 Products)

Synonyms: zgc:112062 antibody, CYSLTR1 antibody, CYSLT1 antibody, CYSLT1R antibody, CYSLTR antibody, HMTMF81 antibody, BB147369 antibody, CysLT1R antibody, Cyslt1 antibody, cysLT1R antibody, cysteinyl leukotriene receptor 1 antibody, cysltr1 antibody, CYSLTR1 antibody, Cysltr1 antibody, LOC100338776 antibody

Background: This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Molecular Weight: 38.541 kDa

Gene ID: 10800

UniProt: Q9Y271