Actl7b antibody
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- Target See all Actl7b Antibodies
- Actl7b (Actin-Like 7b (Actl7b))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Actl7b antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant Protein of human ACTL7B
- Isotype
- IgG
- Top Product
- Discover our top product Actl7b Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Detected only in the testis and, to a lesser extent, in the prostate
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- Actl7b (Actin-Like 7b (Actl7b))
- Alternative Name
- ACTL7B (Actl7b Products)
- Synonyms
- ACTL7B antibody, Tact1 antibody, actin-like 7b antibody, actin like 7B antibody, Actl7b antibody, ACTL7B antibody
- Background
- The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
- Molecular Weight
- 45.234 kDa
- Gene ID
- 10880
- UniProt
- Q9Y614
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