BCL2L2 antibody

Catalog No. ABIN6291794

Product Details anti-BCL2L2 Antibody

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human BCL2L2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, Moderate levels found in thymus, ovary and small intestine, Not detected in salivary gland, muscle or liver, Also expressed in cell lines of myeloid, fibroblast and epithelial origin, Not detected in most lymphoid cell lines

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: BCL2L2 (BCL2L2 Products)

Synonyms: bcl2l2 antibody, BCL2L2 antibody, BCL-W antibody, BCL2-L-2 antibody, BCLW antibody, PPP1R51 antibody, AW048834 antibody, Bcl-w antibody, Gtrgal2 antibody, Gtrosa41 antibody, bclw antibody, c98 antibody, BCL-WEL antibody, BCL-WS antibody, Bclw antibody, bcl-w antibody, bcl2l2-a antibody, bcl2l2-b antibody, xr1 antibody, BCL2 like 2 antibody, BCL2-like 2 antibody, BCL2 like 12 antibody, Bcl2-like 2 antibody, bcl-2-like protein 2 antibody, BCL2-like 2 L homeolog antibody, BCL2L2 antibody, bcl2l2 antibody, BCL2L12 antibody, Bcl2l2 antibody, LOC100154044 antibody, LOC100345100 antibody, bcl2l2.L antibody

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti-and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Molecular Weight: 20.746 kDa

Gene ID: 599

UniProt: Q92843