CD1d antibody

Catalog No. ABIN6292676

Product Details anti-CD1d Antibody

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1d antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human CD1D

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Comment:

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1D (CD1D Products)

Synonyms: CD1A antibody, R3 antibody, CD1D antibody, CD1D1 antibody, CD1d molecule antibody, CD1D antigen, d polypeptide antibody, CD1D antibody

Background: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 37.717 kDa

Gene ID: 912

UniProt: P15813

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process