HBG1 antibody

Catalog No. ABIN6293008

Product Details anti-HBG1 Antibody

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human HBG1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Red blood cells

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for HBG1

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Alternative Name: HBG1 (HBG1 Products)

Synonyms: Hbe1 antibody, Hbb-y antibody, HBGA antibody, HBGR antibody, HSGGL1 antibody, beta-globin antibody, hbb1 antibody, hbga antibody, hbgr antibody, hsggl1 antibody, HBG2 antibody, HBG1 antibody, hemoglobin subunit gamma 1 antibody, hemoglobin subunit gamma 1 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma-1 antibody, Hbg1 antibody, HBG1 antibody, hbg1.L antibody, LOC100982657 antibody

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Molecular Weight: 16.14 kDa

Gene ID: 3047

UniProt: P69891