GREM2 antibody

Catalog No. ABIN6293117

Product Details anti-GREM2 Antibody

Target: GREM2 (Gremlin 2 (GREM2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human GREM2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for GREM2

Target: GREM2 (Gremlin 2 (GREM2))

Alternative Name: GREM2 (GREM2 Products)

Synonyms: prdc antibody, zgc:112207 antibody, RGD1560008 antibody, Gremlin2 antibody, Prdc antibody, CKTSF1B2 antibody, DAND3 antibody, PRDC antibody, gremlin 2, DAN family BMP antagonist antibody, gremlin 2, DAN family BMP antagonist b antibody, gremlin 2, cysteine knot superfamily antibody, GREM2 antibody, grem2b antibody, grem2 antibody, Grem2 antibody

Background: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Molecular Weight: 19.32 kDa

Gene ID: 64388

UniProt: Q9H772