COQ6 antibody
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- Target See all COQ6 Antibodies
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COQ6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human COQ6
- Isotype
- IgG
- Top Product
- Discover our top product COQ6 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Widely expressed
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
- Alternative Name
- COQ6 (COQ6 Products)
- Synonyms
- CGI10 antibody, COQ10D6 antibody, 5930427M12Rik antibody, AW742344 antibody, zgc:153379 antibody, coq6 antibody, coenzyme Q6, monooxygenase antibody, coenzyme Q6 monooxygenase antibody, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial antibody, coenzyme Q6 monooxygenase L homeolog antibody, COQ6 antibody, Coq6 antibody, coq-6 antibody, coq6 antibody, coq6.L antibody
- Background
- The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
- 50.87 kDa
- Gene ID
- 51004
- UniProt
- Q9Y2Z9
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