SUFUH antibody

Catalog No. ABIN6293839

Product Details anti-SUFUH Antibody

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUFUH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human SUFU

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IF 1:50 - 1:200

Comment:

Ubiquitous in adult tissues, Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos, Isoform 1 is detected in fetal brain, lung, kidney and testis, Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Alternative Name: SUFU (SUFUH Products)

Synonyms: CG6054 antibody, Dmel\\CG6054 antibody, SU(FU) antibody, SUFU antibody, Su(Fu) antibody, SuFu antibody, Sufu antibody, su(fu) antibody, sufu antibody, Xsufu antibody, sufuh antibody, sufuxl antibody, PRO1280 antibody, SUFUH antibody, SUFUXL antibody, Su(fu) antibody, dre antibody, fi39e05 antibody, wu:fi39e05 antibody, 2810026F04Rik antibody, b2b273Clo antibody, Suppressor of fused antibody, SUFU negative regulator of hedgehog signaling L homeolog antibody, SUFU negative regulator of hedgehog signaling antibody, suppressor of fused homolog (Drosophila) antibody, Su(fu) antibody, sufu.L antibody, SUFU antibody, sufu antibody, Sufu antibody

Background: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Molecular Weight: 53.947 kDa

Gene ID: 51684

UniProt: Q9UMX1

Pathways: Hedgehog Signaling, Tube Formation, Maintenance of Protein Location