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RNMT antibody

RNMT Reactivity: Human, Rat, Cow, Dog IHC, IF, FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6296036
  • Target See all RNMT Antibodies
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    Reactivity
    • 11
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Cow, Dog
    Host
    • 6
    • 5
    Mouse
    Clonality
    • 6
    • 5
    Monoclonal
    Conjugate
    • 11
    This RNMT antibody is un-conjugated
    Application
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purpose
    Mouse anti-Human/Cow/Dog/Rat TAG-72 Antibody Cocktail [Sodium Azide Free]
    Specificity
    Cytoplasmic and cell surface
    Purification
    A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
    Immunogen
    A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
    Top Product
    Discover our top product RNMT Primary Antibody
  • Application Notes
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    Alternative Name
    mRNA cap guanine-N7 methyltransferase   (RNMT Products)
    Synonyms
    xCMT1 antibody, MET antibody, RG7MT1 antibody, hCMT1c antibody, 2610002P10Rik antibody, AI848273 antibody, Rg7mt1 antibody, mKIAA0398 antibody, rnmt antibody, im:6910566 antibody, wu:fi09c12 antibody, RNA (guanine-7-) methyltransferase L homeolog antibody, RNA guanine-7 methyltransferase antibody, RNA (guanine-7-) methyltransferase antibody, rnmt.L antibody, RNMT antibody, Rnmt antibody, rnmt antibody
    Background

    Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

    Gene Symbol: tag-72  C25A1.3

    Gene ID
    182875
    UniProt
    Q9XVS1
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