IFNA1 antibody

Catalog No. ABIN6296890

This Mouse Monoclonal antibody specifically detects IFNA1 in ELISA and Coat. It exhibits reactivity toward Human.

Quick Overview for IFNA1 antibody (ABIN6296890)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA1 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Product Details anti-IFNA1 Antibody

Purpose: Mouse anti-Human Interferon alpha Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, extracellular (secreted)

Purification: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Immunogen: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Application Details

Application Notes: ELISA: order BSA/azide-free format for coating

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: Interferon alpha-1/13

Background:

Target Description: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Gene Symbol: IFNA1///IFNA13

UniProt: P01562

Pathways: JAK-STAT Signaling, Hepatitis C