SUMO1 antibody

Catalog No. ABIN6297548

The Mouse Monoclonal anti-SUMO1 antibody is suitable to detect SUMO1 in samples from Human, Rat and Mouse. It has been validated for IHC.

Quick Overview for SUMO1 antibody (ABIN6297548)

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUMO1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SUMO1 Antibody

Purpose: Mouse anti-Human/Mouse/Rat SUMO1 Antibody [IHC only]

Specificity: Predominantly nuclear with some cytoplasmic

Purification: Recombinant human protein was used as the immunogen for this SUMO1 antibody.

Immunogen: Recombinant human protein was used as the immunogen for this SUMO1 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for SUMO1

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Alternative Name: Small ubiquitin-related modifier 1

Background:

Target Description: The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability.

Gene Symbol: SUMO1///SMT3C///SMT3H3///UBL1///OK///SW-cl.43

Gene ID: 7341

UniProt: P63165

Pathways: M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway