PAWR antibody

Catalog No. ABIN6298166

The Rabbit Polyclonal anti-PAWR antibody has been validated for . It is suitable to detect PAWR in samples from Human, Mouse and Rat.

Quick Overview for PAWR antibody (ABIN6298166)

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAWR antibody is un-conjugated

Application: Please inquire

Product Details anti-PAWR Antibody

Purpose: Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PAWR

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Alternative Name: Prostate Apoptosis Response protein-4

Background:

Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Gene Symbol: PAWR

Gene ID: 5074

UniProt: Q96IZ0