PTPN11 antibody (Protein tyrosine Phosphatase, Non-Receptor Type 11)

Details for Product anti-PTPN11 Antibody No. ABIN6298563
Antigen
  • BPTP3
  • CFC
  • NS1
  • PTP-1D
  • PTP2C
  • SH-PTP2
  • SH-PTP3
  • SHP2
  • 2700084A17Rik
  • AW536184
  • PTP1D
  • SAP-2
  • SHP-2
  • Shp2
  • Syp
  • SYP
  • bptp3
  • cfc
  • ns1
  • ptp-2
  • ptp2c
  • ptpn11
  • ptpn11-a
  • ptpn11-b
  • shp-2
  • shp2
  • fa14b09
  • wu:fa14b09
  • wu:fi24f03
  • zgc:55388
  • zgc:63553
  • protein tyrosine phosphatase, non-receptor type 11
  • protein tyrosine phosphatase, non-receptor type 11 S homeolog
  • protein tyrosine phosphatase, non-receptor type 11, a
  • protein tyrosine phosphatase, non-receptor type 11, b
  • PTPN11
  • Ptpn11
  • ptpn11.S
  • ptpn11a
  • ptpn11b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
429
270
249
11
11
10
10
10
10
9
6
4
3
3
1
Host
Rabbit
388
40
7
2
1
Clonality
Polyclonal
Conjugate
This PTPN11 antibody is un-conjugated
20
14
14
14
14
14
14
10
9
6
5
5
3
3
3
3
3
2
2
Application
315
148
129
69
39
33
31
21
10
7
6
6
3
2
1
1
1
1
Options
Purpose Rabbit Anti-SH-PTP2 Antibody,
Plasmids, Primers & others Plasmids, Primers & others PTPN11 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SH-PTP2 (PTPN11 Antibody Abstract)
Background

Target Description: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

Gene Symbol: PTPN11

Gene ID 5781
UniProt Q06124
Pathways JAK-STAT Signaling, RTK Signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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