HIST2H2AC antibody (Middle Region)

Catalog No. ABIN630176

Product Details anti-HIST2H2AC Antibody

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AC antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: HIST2 H2 C antibody was raised against the middle region of HIST2 2 C

Purification: Purified

Immunogen: HIST2 H2 C antibody was raised using the middle region of HIST2 2 C corresponding to a region with amino acids IPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHKAKSK

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HIST2H2AC Blocking Peptide, catalog no. 33R-4098, is also available for use as a blocking control in assays to test for specificity of this HIST2H2AC antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HIST0 0 C antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for HIST2H2AC

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Alternative Name: HIST2H2AC (HIST2H2AC Products)

Synonyms: HIST2H2AC antibody, H2A antibody, H2A-GL101 antibody, H2A/q antibody, H2AFQ antibody, H2a-613b antibody, RGD1560965 antibody, histone cluster 1, H2A, IV antibody, histone cluster 2 H2A family member c antibody, histone cluster 2, H2ac antibody, HIST1H2A4 antibody, HIST2H2AC antibody, Hist2h2ac antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.

Molecular Weight: 14 kDa (MW of target protein)