IVNS1ABP antibody (N-Term)
Quick Overview for IVNS1ABP antibody (N-Term) (ABIN630725)
Target
See all IVNS1ABP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- Influenza Virus Ns1 A Binding Protein antibody was raised against the N terminal of IVNS1 BP
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Cross-Reactivity
- Human, Dog (Canine)
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Purification
- Affinity purified
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Immunogen
- Influenza Virus Ns1 A Binding Protein antibody was raised using the N terminal of IVNS1 BP corresponding to a region with amino acids RAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK
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Application Notes
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WB: 1 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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Influenza Virus Ns1A Binding Protein Blocking Peptide, (ABIN5614193), is also available for use as a blocking control in assays to test for specificity of this Influenza Virus Ns1A Binding Protein antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IVNS0 BP antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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Alternative Name
- Influenza Virus Ns1A Binding Protein
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Target Type
- Influenza Protein
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Background
- This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.
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Molecular Weight
- 72 kDa (MW of target protein)
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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